Direct installation of sulfur moiety into bioactive N-heterocyclic compounds

Aryl and heteroaryl sulfides are common structural motifs found in many bioactive natural products and drugs. These thio-substituted scaffolds are also important building blocks in synthesis, material science and pharmaceutical industry. Throughout the past two decades, several strategies to construct C−S bond; for instance, conventional synthesis, transition metal-catalyzed or metal-free mediated C−S bond cross coupling … Continue reading Direct installation of sulfur moiety into bioactive N-heterocyclic compounds